Set up the comparison
Write the stereochemical form into the item name and acceptance documents. Cross-check it against the English name, identifier and analytical method.
Measurements to record
Stereochemistry (Chiral identification). Compare against a reference or under agreed optical rotation conditions. Record sample temperature and solvent. Principal component assay (% by mass). Identify the analyte, dry or as-received basis and method. Do not substitute a theoretical conversion for an incoming release result. Record the sample ID and method revision for repeat testing.
Interpreting the results
If a quote says only alanine, resolve the identity before approving a sample. Total assay alone does not distinguish L, D and DL material.
What to record
- Stereochemistry
- English name
- Identifier
- Analytical test
- Approved sample revision
Technical references
Products and processes
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